Quran and Science of Embroyology

A group of Muslim Scholars, under the direction of an eminent Yemani Scholar, Sheikh Abdul Majid Azzindani, collected information concerning embryology1 and other sciences in the Qur’an and undisputed Hadith2 and translated it into English. They then followed the Qur’anic advice: “If ye realise this not, ask of those who possess the Message.” [Al-Qur’an 16:43 & 21:7]

All the information from the Qur’an and the undisputed Hadith concerning embryology so gathered, after being translated into English and presented to Prof. (Dr.) Keith Moore, Professor of Embryology and Chairman of the Department of Anatomy at the University of Toronto, in Canada. At present he is one of the highest authorities in the field of Embryology. He was asked to give his opinion regarding the material presented to him. After carefully examining it, Dr. Moore said that most of the information concerning embryology mentioned in the Qur’an and the undisputed Hadith is in perfect conformity with modern discoveries in the field of embryology and does not conflict with them in any way.

He added that there were a few verses however, on whose scientific accuracy he could not comment. He could not say whether the statements were true or false, since he was himself unaware of the information contained therein. There was also no mention of this information in modern writings and studies on embryology. One such verse is: “Proclaim! (or Read!) In the name of thy Lord and Cherisher, Who created – Created man, out of a (mere) clot of congealed blood.” [Al-Qur’an 96:1-2]

The Arabic word alaq, besides meaning a congealed clot of blood, also means something that clings, a leech-like substance. Dr. Keith Moore had no knowledge whether an embryo in the initial stages appears like a leech. To check this out he studied the initial stage of the embryo under a very powerful microscope and compared what he observed with the diagram of a leech. He was astonished at the striking resemblance between the two! In the same manner, he acquired more information on embryology, that was hitherto not known to him, from the Qur’an. Dr. Keith Moore answered about eighty questions dealing with embryological data mentioned in the Qur’an and Hadith. Noting that the information contained in the Qur’an and Hadith was in full agreement with the latest discoveries in the field of embryology, Prof. Moore said, “If I was asked these questions thirty years ago, I would not have been able to answer half of them for lack of scientific information”.

If we keep on examining the facts announced to us in the Qur’an about the formation of human beings, we again encounter some very important scientific miracles.

When the sperm of the male unites with the ovum of the female, the essence of the baby to be born is formed. This single cell, known as a “zygote” in biology, will instantly start to reproduce by dividing, and eventually become a “piece of flesh” called an embryo. This of course can only be seen by human beings with the aid of a microscope.

The embryo, however, does not spend its developmental period in a void. It clings to the uterus just like roots that are firmly fixed to the earth by their tendrils. Through this bond, the embryo can obtain the substances essential to its development from the mother’s body.

Here, at this point, a very significant miracle of the Qur’an is revealed. While referring to the embryo developing in the mother’s womb, God uses the word alaq in the Qur’an:

Certainly, the use of such an appropriate word for the embryo developing in the mother’s womb, proves once again that the Qur’an is a revelation from God, the Lord of all the Worlds.

In 1981, during the Seventh Medical Conference in Dammam, Saudi Arabia, Dr. Moore said, “It has been a great pleasure for me to help clarify statements in the Qur’an about human development. It is clear to me that these statements must have come to Muhammad from God or Allah, because almost all of this knowledge was not discovered until many centuries later. This proves to me that Muhammad must have been a messenger of God or Allah”.2 Dr. Keith Moore had earlier authored the book, ‘The Developing Human’. After acquiring new knowledge from the Qur’an, he wrote, in 1982, the 3rd edition of the same book, ‘The Developing Human’. The book was the recipient of an award for the best medical book written by a single author. This book has been translated into several major languages of the world and is used as a textbook of embryology in the first year of medical studies. Dr. Joe Leigh Simpson, Chairman of the Department of Obstetrics and Gynaecology, at the Baylor College of Medicine, Houston, U.S.A., proclaims: “…these Hadiths, sayings of Muhammad (pbuh), could not have been obtained on the basis of the scientific knowledge that was available at the time of the writer (implying in the 7th century). It follows that not only is there no conflict between genetics and religion (implying Islam) but in fact religion (Islam) may guide science by adding revelation to some of the traditional scientific approaches . . . there exist statements in the Qur’an shown centuries later to be valid which support knowledge in the Qur’an having been derived from God.”

Drop Emitted from Between the Back Bone & the Ribs

The Holy Qur’an says “Now let man but think from what he is created! He is created from a drop emitted – Proceeding from between the back bone and the ribs.” [Al-Qur’an 86:5-7]

In embryonic stages, the reproductive organs of the male and female, i.e. the testicles and the ovaries, begin their development near the kidney between the spinal column and the eleventh and twelfth ribs. Later they descend; the female gonads (ovaries) stop in the pelvis while the male gonads (testicles) continue their descent before birth to reach the scrotum through the inguinal canal. Even in adulthood after the descent of the reproductive organs, these organs receive their nerve supply and blood supply from the Abdominal Aorta, which is in the area between the backbone (spinal column) and the ribs. The lymphatic drainage and the venous return also go to the same area.

NUTFAH – MINUTE QUANTITY OF LIQUID

The Glorious Qur’an mentions no less than eleven times that the human being is created from nutfah, which means a minute quantity of liquid or a trickle of liquid that remains after emptying a cup. This is mentioned in several verses of the Qur’an including 22:5 and 23:13 Science has confirmed in recent times that only one out of an average of three million sperms is required for fertilising the ovum. This means that only 1/3 millionth part or 0.00003% of the quantity of sperms that are emitted is required for fertilisation.

SULALAH – QUINTESSENCE OF LIQUID

“And made his progeny from a quintessence of the nature of a fluid despised.” [Al-Qur’an 32:8] The Arabic word sulaalah means quintessence or the best part of a whole. We have come to know now that only one single spermatozoon that penetrates the ovum is required for fertilization, out of the several million produced by man. That one spermatozoon out of several million, is referred to in the Qur’an as sulaalah. We have also come to know now that only one ovum is fertilized out of the tens of thousand produced by the female. That one ovum out of tens of thousand is also refered to in the Qur’an as Sulaalah. This word also means gentle extraction from a fluid. The fluid refers to both male and female germinal fluids containing gametes. Both ovum and sperm are gently extracted from their environments in the process of fertilization..

NUTFATUN AMSHAAJ – MINGLED LIQUIDS

“Verily We created man from a drop of mingled sperm.” [Al-Qur’an 76:2] The Arabic word nutfatin amshaajin means mingled liquids. According to some commentators of the Qur’an, mingled liquids refers to the male or female agents or liquids. After mixture of male and female gamete, the zygote still remains nutfah. Mingled liquids can also refer to spermatic fluid that is formed of various secretions that come from various glands. Therefore, nutfatin amshaaj, i.e. a minute quantity of mingled fluids refers to the male and female gametes (germinal fluids or cells) and part of the surrounding fluids.

The Sex of the Baby

Until fairly recently, it was thought that a baby’s sex was determined by the mother’s cells. Or at least, it was believed that the sex was determined by the male and female cells together. But we are given different information in the Qur’an, where it is stated that masculinity or femininity is created out of “a drop of sperm which has been ejected”.

“That He did create in pairs – male and female, from a seed when lodged (in its place).” [Surah Najm 53:45-46]

“Was he not a drop of sperm emitted (in lowly form)? “Then did he become a clinging clot; then did (Allah) make and fashion (him) in due proportion. “And of him He made two sexes, male and female.” [Surah Qiyamah 75:37-39]

The developing disciplines of genetics and molecular biology have scientifically validated the accuracy of this information given by God in the Qur’an. It is now understood that sex is determined by the sperm cells from the male, and that the female has no role in this process.

Chromosomes are the main elements in determining sex. Two of the 46 chromosomes that determine the structure of a human being are identified as the sex chromosomes. These two chromosomes are called “XY” in males, and “XX” in females, because the shapes of the chromosomes resemble these letters.

The Y chromosome carries the genes that code for masculinity, while the X chromosome carries the genes that code for femininity.

The formation of a new human being begins with the cross combination of one of these chromosomes, which exist in males and females in pairs. In females, both components of the sex cell, which divides into two during ovulation, carry X chromosomes. The sex cell of a male, on the other hand, produces two different kinds of sperm, one that contains X chromosomes and the other Y chromosomes. If an X chromosome from the female unites with a sperm that contains an X chromosome, then the baby is female. If it unites with the sperm that contains a Y chromosome, the baby is male.

In other words, a baby’s sex is determined by which chromosome from the male unites with the female’s ovum.

None of this was known until the discovery of genetics in the 20th century. Indeed, in many cultures, it was believed that a baby’s sex was determined by the female’s body. That was why women were blamed when they gave birth to girls.

Fourteen centuries before human genes were discovered, however, the Qur’an revealed information that denies this superstition, and referred to the origin of sex lying not with women, but with the semen coming from men.

The sex of a foetus is determined by the nature of the sperm and not of the ovum. The sex of the child, whether female or male, depends on whether the 23rd pair of chromosomes is XX or XY respectively. Primarily, sex determination occurs at fertilization and depends upon the type of sex chromosome in the sperm that fertilizes an ovum. If it is an ‘X’ bearing sperm that fertilizes the ovum, the foetus is a female and if it is a ‘Y’ bearing sperm then the foetus is a male.The Arabic word nutfah means a minute quantity of liquid and tumnaa means ejaculated or planted. Therefore nutfah specifically refers to sperm because it is ejaculated. The Qur’an says:Here again it is mentioned that a small quantity (drop) of sperm (indicated by the word nutfatan min maniyyin) which comes from the man is responsible for the sex of the foetus. Mothers-in-law in the Indian subcontinent, usually prefer having male grandchildren and often blame their daughters-in-law if the child is not a boy. If only they knew that the determining factor is the nature of the male sperm and not the female ovum! If they were to blame anybody, they should rather blame their sons, not their daughters-in-law, since both the Qur’an and Science hold that it is the male fluid that is responsible for the sex of the child!

Three Dark Stages of the Baby in the Womb

In the Qur’an, it is related that man is created in a three-stage process in the mother’s womb:

“He makes you, in the wombs of your mothers, in stages, one after another, in three veils of darkness.” [Al-Qur’an 39:6]

The expression fee thulumatin thalathin, translated into English as “a threefold darkness,” indicates three dark regions involved during the development of the embryo. These are:

a) The darkness of the abdomen

b) The darkness of the womb

c) The darkness of the placenta

As we have seen, modern biology has revealed that the embryological development of the baby takes place in the manner revealed in the verse, in three dark regions. Moreover, advances in the science of embryology show that these regions consist of three layers each.

The lateral abdominal wall comprises three layers: the external oblique, the internal oblique, and transverses abdominis muscles.

Similarly, the wall of the womb also consists of three layers: the epimetrium, the myometrium and the endometrium.

Similarly again, the placenta surrounding the embryo also consists of three layers: the amnion (the internal membrane around the fetus), the chorion (the middle amnion layer) and the decidua (outer amnion layer.)

It is also pointed out in this verse that a human being is created in the mother’s womb in three distinct stages. Indeed, modern biology has revealed that the baby’s embryological development takes place in three distinct regions in the mother’s womb.

Today, in all the embryology textbooks studied in faculties of medicine, this subject is taken as an element of basic knowledge. For instance in Basic Human Embryology, a fundamental reference text in the field of embryology, this fact is stated as follows:

“The life in the uterus has three stages: pre-embryonic; first two and a half weeks, embryonic; until the end of the eight week, and fetal; from the eight week to labor.”

These phases refer to the different developmental stages of a baby. In brief, the main characteristics of these developmental stages are as follows:

– Pre-embryonic stage

In this first phase, the zygote grows by division, and when it becomes a cell cluster, it buries itself in the wall of the uterus. While they continue growing, the cells organize themselves in three layers.

– Embryonic Stage

The second phase lasts for five and a half weeks, during which the baby is called an “embryo”. In this stage, the basic organs and systems of the body start to appear from the cell layers.

– Fetal stage

From this stage on, the embryo is called a “fetus”. This phase begins at the eighth week of gestation and lasts until the moment of birth. The distinctive characteristic of this stage is that the fetus looks just like a human being, with its face, hands and feet. Although it is only 3 cm. long initially, all of its organs have become apparent. This phase lasts for about 30 weeks, and development continues until the week of delivery.

Information on the development in the mother’s womb became available only after observations with modern devices. Yet, just like many other scientific facts, these pieces of information are imparted in the verses of the Qur’an in a miraculous way. The fact that such detailed and accurate information was given in the Qur’an at a time when people had scarce information on medical matters is clear evidence that the Qur’an is the word of God.

The wrapping of muscles over the bones

Another important aspect of the information given in the verses of the Qur’an is the developmental stages of a human being in the mother’s womb. It is stated in the verses that in the mother’s womb, the bones develop first, and then the muscles form which wrap around them:

“Man We did create from a quintessence (of clay); then We placed him as (a drop of) sperm in a place of rest, firmly fixed; then We made the sperm into a clot of congealed blood; then of that clot We made a (foetus) lump; then We made out of that lump bones and clothed the bones with flesh; then We developed out of it another creature. so blessed be Allah, the Best to create!” [Surah Muminun23:12-14]

Embryology is the branch of science that studies the development of the embryo in the mother’s womb. Until very recently, embryologists assumed that the bones and muscles in an embryo developed at the same time. Yet, advanced microscopic research conducted by virtue of new technological developments has revealed that the revelation of the Qur’an is word for word correct.

These observations at the microscopic level showed that the development inside the mother’s womb takes place in just the way it is described in the verses. First, the cartilage tissue of the embryo ossifies. Then muscular cells that are selected from amongst the tissue around the bones come together and wrap around the bones.

This event is described in a scientific publication titledDeveloping Humanin the following words:

“… The shape of the skeleton determines the general appearance of the embryo in the bones stage during the 7th week; muscles do not develop at the same time but their development follows soon after. The muscles take their positions around the bones throughout the body and therefore Clothe the bones. Thus, the muscles take their well known forms and structures… The stage of clothing with muscle occurs during the 8th week…”

In short, man’s developmental stages as described in the Qur’an are in perfect harmony with the findings of modern embryology.

EMBRYOLOGICAL STAGES

“Man We did create from a quintessence (of clay); then We placed him as (a drop of) sperm in a place of rest, firmly fixed; then We made the sperm into a clot of congealed blood; then of that clot We made a (foetus) lump; then We made out of that lump bones and clothed the bones with flesh; then We developed out of it another creature. so blessed be Allah, the Best to create!” [Al-Qur’ an 23:12-14]

In this verse Allah states that man is created from a small quantity of liquid which is placed in a place of rest, firmly fixed (well established or lodged) for which the Arabic word qaraarin makeen is used. The uterus is well protected from the posterior by the spinal column supported firmly by the back muscles. The embryo is further protected by the amniotic sac containing the amniotic fluid. Thus the foetus has a well protected dwelling place. This small quantity of fluid is made into alaqah, meaning something which clings. It also means a leech-like substance. Both descriptions are scientifically acceptable as in the very early stages the foetus clings to the wall and also appears to resemble the leech in shape. It also behaves like a leech (blood sucker) and acquires its blood supply from the mother through the placenta. The third meaning of the word alaqah is a blood clot. During this alaqah stage, which spans the third and fourth week of pregnancy, the blood clots within closed vessels. Hence the embryo acquires the appearance of a blood clot in addition to acquiring the appearance of a leech. Compare the readily available Qur’anic knowledge with Man’s struggle with scientific findings: In 1677, Hamm and Leeuwenhoek were the first scientists to observe human sperm cells (spermatozoa) through a microscope. They thought that a sperm cell contained a miniature human being which grew in the uterus to form a newborn. This was known as the perforation theory.

When scientists discovered that the ovum was bigger than the sperm, it was thought by scientists like De Graf and others that the foetus existed in a miniature form in the ovum. Later, in the 18th century, Maupertuis propagated the theory of biparental inheritance. The alaqah is transformed into mudghah which means ‘something that is chewed (having teeth marks)’ and also something that is tacky and small which can be put in the mouth like gum. Both these explanations are scientifically correct. Prof. Keith Moore took a piece of plaster seal and made it into the size and shape of the early stage of foetus and chewed it between the teeth to make it into a mudghah. He compared this with the photographs of the early stage of foetus. The teeth marks resembled the ‘somites’ which is the early formation of the spinal column. This mudghah is transformed into bones (izâm). The bones are clothed with intact flesh or muscles (lahm). Then Allah makes it into another creature. Prof. Marshall Johnson who is one of the leading scientists in the USA, and is the head of the Department of Anatomy and Director of the Daniel Institute at the Thomas Jefferson University in Philadelphia in the USA, was asked to comment on the verses of the Qur’an dealing with embryology. At first he said that the verses of the Qur’an describing the embryological stages cannot be a coincidence. It was probable that Muhammad (pbuh) had a powerful microscope. On being reminded that the Qur’an was revealed 1400 years ago, and microscopes were invented many centuries after the time of Prophet Muhammad (pbuh), Prof. Johnson laughed and admitted that the first microscope invented could not magnify more than 10 times and could not show a clear picture. Later he said: “I see nothing here in conflict with the concept that Divine intervention was involved when Muhammad (pbuh) recited the Qur’an.”1 According to Dr. Keith Moore, the modern classification of embryonic development stages which is adopted throughout the world, is not easily comprehensible, since it identifies stages on a numerical basis i.e. stage 1, stage 2, etc.

On the other hand, the divisions revealed in the Qur’an are based on distinct and easily identifiable forms or shapes, which the embryo passes through. These are based on different phases of pre-natal development and provide elegant scientific descriptions that are comprehensible and practical. Embryological stages of human development have also been described in the following verses: “Was he not a drop of sperm emitted (in lowly form)? Then did he become a clinging clot; then did (Allah) make and fashion (him) in due proportion. and of him He made two sexes, male and female.” [Al-Qur’an 75:37-39]

“Him Who created thee, fashioned thee in due proportion, and gave thee a just bias; in whatever Form He wills, does He put thee together.” [Al-Qur’an 82:7-8]

EMBRYO PARTLY FORMED AND PARTLY UNFORMED

At the mudghah stage, if an incision is made in the embryo and the internal organ is dissected, it will be seen that most of them are formed while the remaining are not yet completely formed. According to Prof. Johnson, if we describe the embryo as a complete creation, then we are only describing that part which is already created. If we describe it as an incomplete creation, then we are only describing that part which is not yet created. So, is it a complete creation or an incomplete creation? There is no better description of this stage of embryogenesis than the Qur’anic description, “partly formed and partly unformed”, as in the following verse: “We created you out of dust, then out of sperm, then out of a leech-like clot, then out of a morsel of flesh, partly formed and partly unformed that We may manifest (Our Power) to you.” [Al-Qur’an 22:5] Scientifically we know that at this early stage of development there are some cells which are differentiated and there are some cells that are undifferentiated – some organs are formed and yet others unformed.

SENSE OF HEARING AND SIGHT

The first sense to develop in a developing human embryo is hearing. The foetus can hear sounds after the 24th week. Subsequently, the sense of sight is developed and by the 28th week, the retina becomes sensitive to light. The Qur’an explains it thus: “And He gave you (the faculties of) hearing and sight and feeling (and understanding).” [Al-Qur’an 32:9]

“Verily We created man from a drop of mingled sperm, in order to try him: so We gave him (the gifts), of Hearing and Sight.” [Al-Qur’an 76:2]

“It is He Who has created for you (the faculties of) hearing, sight, feeling and understanding: little thanks it is ye give!” [Al-Qur’an 23:78]

In all these verses the sense of hearing is mentioned before that of sight. Thus the Qur’anic description matches perfectly with the discoveries in modern embryology.

Allah knows the best